STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102352197Methyltranfer_dom domain-containing protein. (272 aa)    
Predicted Functional Partners:
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
   
 0.693
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 0.686
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.660
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.618
RPS2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
    
 0.607
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
    
 
 0.604
ERG28
Ergosterol biosynthesis 28 homolog.
    
 
 0.603
TRMT112
tRNA methyltransferase subunit 11-2.
   
 0.583
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.569
H4C11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.559
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.