Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC102358202Tyrosine-protein kinase receptor. (838 aa)    
Predicted Functional Partners:
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.954
H3AGX2_LATCH
Recep_L_domain domain-containing protein.
 
      0.900
INSR
Uncharacterized protein.
 
      0.900
IRS1
Insulin receptor substrate 1.
    
 0.876
PTPN1
Tyrosine-protein phosphatase non-receptor type.
    
 0.850
IRS2
Insulin receptor substrate 2.
    
 0.836
PTPN2
Tyrosine-protein phosphatase non-receptor type.
    
 0.744
ESR2
Estrogen receptor 2.
    
 0.739
IRS4
Insulin receptor substrate 4.
    
 0.699
H3B2S3_LATCH
Uncharacterized protein.
    
 0.699
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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