Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (304 aa)    
Predicted Functional Partners:
HBZ
Hemoglobin subunit zeta; Belongs to the globin family.
   
0.998
LOC102354911
Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues.
   
0.973
APOB
Apolipoprotein B.
    
 0.871
ZRANB2
Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family.
    
 
 0.813
CD74
CD74 molecule.
    
 
 0.776
MASP1
Mannan binding lectin serine peptidase 1.
    
 0.713
LOC102362749
Interfer-bind domain-containing protein.
      
 0.705
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
      
 0.685
ATP2B4
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.677
RPL32
Ribosomal protein L32.
      
 0.626
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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