TBX6 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

TBX6

Uncharacterized protein. (101 aa)

Predicted Functional Partners:

MEOX1

0.639

MSGN1

0.628

FGF8

0.534

LRP2

0.465

RBPJ

0.433

WNT3

0.423

WNT3A

0.423

FOXD2

0.404

CHRD

0.403

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRD	FGF8	ENSLACP00000000821	ENSLACP00000007843	Chordin; Belongs to the chordin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.638
CHRD	MSGN1	ENSLACP00000000821	ENSLACP00000016994	Chordin; Belongs to the chordin family.	Mesogenin 1.	0.447
CHRD	TBX6	ENSLACP00000000821	ENSLACP00000005391	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.403
FGF8	CHRD	ENSLACP00000007843	ENSLACP00000000821	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Chordin; Belongs to the chordin family.	0.638
FGF8	TBX6	ENSLACP00000007843	ENSLACP00000005391	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.534
FGF8	WNT3	ENSLACP00000007843	ENSLACP00000008791	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.559
FGF8	WNT3A	ENSLACP00000007843	ENSLACP00000019786	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.528
FOXD2	LRP2	ENSLACP00000009751	ENSLACP00000021820	Fork-head domain-containing protein.	LDL receptor related protein 2.	0.501
FOXD2	TBX6	ENSLACP00000009751	ENSLACP00000005391	Fork-head domain-containing protein.	Uncharacterized protein.	0.404
LRP2	FOXD2	ENSLACP00000021820	ENSLACP00000009751	LDL receptor related protein 2.	Fork-head domain-containing protein.	0.501
LRP2	TBX6	ENSLACP00000021820	ENSLACP00000005391	LDL receptor related protein 2.	Uncharacterized protein.	0.465
LRP2	WNT3	ENSLACP00000021820	ENSLACP00000008791	LDL receptor related protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.446
LRP2	WNT3A	ENSLACP00000021820	ENSLACP00000019786	LDL receptor related protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.446
MEOX1	TBX6	ENSLACP00000008656	ENSLACP00000005391	Mesenchyme homeobox 1.	Uncharacterized protein.	0.639
MSGN1	CHRD	ENSLACP00000016994	ENSLACP00000000821	Mesogenin 1.	Chordin; Belongs to the chordin family.	0.447
MSGN1	TBX6	ENSLACP00000016994	ENSLACP00000005391	Mesogenin 1.	Uncharacterized protein.	0.628
RBPJ	TBX6	ENSLACP00000008245	ENSLACP00000005391	Recombination signal binding protein for immunoglobulin kappa J region.	Uncharacterized protein.	0.433
TBX6	CHRD	ENSLACP00000005391	ENSLACP00000000821	Uncharacterized protein.	Chordin; Belongs to the chordin family.	0.403
TBX6	FGF8	ENSLACP00000005391	ENSLACP00000007843	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.534
TBX6	FOXD2	ENSLACP00000005391	ENSLACP00000009751	Uncharacterized protein.	Fork-head domain-containing protein.	0.404