Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCN1BSodium voltage-gated channel beta subunit 1. (221 aa)    
Predicted Functional Partners:
SCN2B
Sodium voltage-gated channel beta subunit 2.
  
0.996
SCN4B
Sodium voltage-gated channel beta subunit 4.
   
 0.992
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.991
SCN10A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.978
H2ZUL4_LATCH
Uncharacterized protein.
   
 0.969
SCN8A
Sodium voltage-gated channel alpha subunit 8.
   
 0.947
LOC102360076
Protein kinase domain-containing protein.
     
  0.900
LOC102362951
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
     
  0.900
CAMK2G
Protein kinase domain-containing protein.
     
 0.900
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
  0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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