Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHOX2BPaired like homeobox 2B. (287 aa)    
Predicted Functional Partners:
PHOX2A
Paired like homeobox 2A.
   
 
 0.844
DBH
Dopamine beta-hydroxylase.
   
 
 0.777
H3ABV0_LATCH
Tyrosine hydroxylase.
   
  
 0.771
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.691
HAND2
Heart and neural crest derivatives expressed 2.
   
 
 0.682
LOC102350473
Tyrosine hydroxylase 2.
   
  
 0.643
PRDM12
PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
      
 0.641
GATA3
GATA binding protein 3.
    
 
 0.614
MYO1H
Myosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.608
GPR4
G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family.
      
 0.605
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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