STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3A6Z2_LATCHGMP_PDE_delta domain-containing protein. (185 aa)    
Predicted Functional Partners:
ARL3
ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.
    
 0.939
H3A466_LATCH
ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.903
H3BAE0_LATCH
ADP ribosylation factor like GTPase 3, like 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.869
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.702
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
  
   
 0.659
RP2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
     
 0.640
NPHP3
Nephronophthisis 3.
    
 0.572
TBCC
Tubulin folding cofactor C.
     
 0.570
PPIE
Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
      
 0.523
C5orf30
Chromosome 5 open reading frame 30.
    
 
 0.493
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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