Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A742_LATCHMANEC domain-containing protein. (342 aa)    
Predicted Functional Partners:
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
 
 0.794
DDX28
DEAD-box helicase 28.
    
 
 0.700
KLHL42
Kelch like family member 42.
      
 0.680
CCDC91
Coiled-coil domain containing 91.
    
 
 0.676
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.655
TTC38
Tetratricopeptide repeat domain 38.
      
 0.642
FAR2
Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
      
 0.626
BMS1
BMS1 ribosome biogenesis factor.
      
 0.613
ERGIC2
ERGIC and golgi 2.
      
 0.592
LOC102363236
Uncharacterized protein.
      
 0.592
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.