Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PWWP2BPWWP domain containing 2B. (577 aa)    
Predicted Functional Partners:
TRIP11
Thyroid hormone receptor interactor 11.
      
 0.833
TMEM251
Transmembrane protein 251.
      
 0.819
PRDM11
SET domain-containing protein.
      
 0.804
ELFN1
Extracellular leucine rich repeat and fibronectin type III domain containing 1.
      
 0.731
MYCBP2
MYC binding protein 2.
      
 0.725
SOCS6
Suppressor of cytokine signaling 6.
      
 0.674
RLIM
Ring finger protein, LIM domain interacting.
      
 0.641
CPNE1
Copine I.
      
 0.641
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
      
 0.639
C2orf68
Chromosome 2 open reading frame 68.
      
 0.636
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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