Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1821 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.769
EFCAB7
EF-hand calcium binding domain 7.
    
 0.745
BCO1
Beta-carotene oxygenase 1.
     
 0.701
RND3
Rho family GTPase 3.
    
  0.678
RHOV
Ras homolog family member V.
    
  0.678
SORBS3
Sorbin and SH3 domain containing 3.
    
 0.656
SORBS1
Sorbin and SH3 domain containing 1.
    
 0.656
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
    
 
 0.645
H3B919_LATCH
IQ motif containing E.
     
 0.642
TMEM54
Transmembrane protein 54.
    
 
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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