Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXW2F-box and WD repeat domain containing 2. (468 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.987
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.974
RBX1
Ring-box 1.
    
 0.951
TBC1D31
TBC1 domain family member 31.
    
 0.825
TTLL11
Tubulin tyrosine ligase like 11.
      
 0.811
FBXL15
F-box and leucine rich repeat protein 15.
    
 0.794
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.777
H3A8H2_LATCH
Uncharacterized protein.
   
 0.766
SKP2
S-phase kinase associated protein 2.
    
 0.751
PSMD5
Proteasome 26S subunit, non-ATPase 5.
      
 0.740
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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