AARS1 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AARS1

Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (968 aa)

Predicted Functional Partners:

IARS1

0.990

GARS1

0.989

YARS1

0.988

LARS1

0.942

EPRS1

0.932

NARS1

0.921

LOC102360705

0.919

DARS1

0.913

QARS1

0.909

IARS2

0.909

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AARS1	DARS1	ENSLACP00000005503	ENSLACP00000011361	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Aspartyl-tRNA synthetase.	0.913
AARS1	EPRS1	ENSLACP00000005503	ENSLACP00000013372	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Glutamyl-prolyl-tRNA synthetase.	0.932
AARS1	GARS1	ENSLACP00000005503	ENSLACP00000003138	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Glycyl-tRNA synthetase.	0.989
AARS1	IARS1	ENSLACP00000005503	ENSLACP00000021524	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.990
AARS1	IARS2	ENSLACP00000005503	ENSLACP00000014392	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.909
AARS1	LARS1	ENSLACP00000005503	ENSLACP00000010578	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.942
AARS1	LOC102360705	ENSLACP00000005503	ENSLACP00000021270	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Threonyl-tRNA synthetase-like 2.	0.919
AARS1	NARS1	ENSLACP00000005503	ENSLACP00000019343	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Asparaginyl-tRNA synthetase.	0.921
AARS1	QARS1	ENSLACP00000005503	ENSLACP00000006386	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.909
AARS1	YARS1	ENSLACP00000005503	ENSLACP00000017686	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	Tyrosine--tRNA ligase.	0.988
DARS1	AARS1	ENSLACP00000011361	ENSLACP00000005503	Aspartyl-tRNA synthetase.	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	0.913
DARS1	EPRS1	ENSLACP00000011361	ENSLACP00000013372	Aspartyl-tRNA synthetase.	Glutamyl-prolyl-tRNA synthetase.	0.999
DARS1	GARS1	ENSLACP00000011361	ENSLACP00000003138	Aspartyl-tRNA synthetase.	Glycyl-tRNA synthetase.	0.914
DARS1	IARS1	ENSLACP00000011361	ENSLACP00000021524	Aspartyl-tRNA synthetase.	Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.996
DARS1	IARS2	ENSLACP00000011361	ENSLACP00000014392	Aspartyl-tRNA synthetase.	Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.904
DARS1	LARS1	ENSLACP00000011361	ENSLACP00000010578	Aspartyl-tRNA synthetase.	Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.993
DARS1	NARS1	ENSLACP00000011361	ENSLACP00000019343	Aspartyl-tRNA synthetase.	Asparaginyl-tRNA synthetase.	0.434
DARS1	QARS1	ENSLACP00000011361	ENSLACP00000006386	Aspartyl-tRNA synthetase.	Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.997
DARS1	YARS1	ENSLACP00000011361	ENSLACP00000017686	Aspartyl-tRNA synthetase.	Tyrosine--tRNA ligase.	0.995
EPRS1	AARS1	ENSLACP00000013372	ENSLACP00000005503	Glutamyl-prolyl-tRNA synthetase.	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.	0.932

page 1 of 6

Server load: low (8%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About