Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC85ACoiled-coil domain containing 85A. (387 aa)    
Predicted Functional Partners:
ARHGAP23
Rho GTPase activating protein 23.
    
 
 0.666
ARHGAP21
Rho GTPase activating protein 21.
    
 
 0.664
CARD19
Caspase recruitment domain family, member 19.
      
 0.629
BUD13
BUD13 homolog.
      
 0.607
ZNF622
Zinc finger protein 622.
      
 0.594
DTD2
D-aminoacyl-tRNA deacylase 2.
      
 0.590
CCDC85C
Coiled-coil domain containing 85C.
      
 0.588
IL10RB
Uncharacterized protein.
   
 
 0.587
FAM131B
Family with sequence similarity 131 member B.
      
 0.587
NUP43
Nucleoporin 43.
      
 0.586
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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