Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
COA7Cytochrome c oxidase assembly factor 7 (putative). (228 aa)    
Predicted Functional Partners:
TACO1
Translational activator of cytochrome c oxidase I.
     
 0.859
MGME1
Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.
      
 0.744
CHCHD4
Coiled-coil-helix-coiled-coil-helix domain containing 4.
   
 
 0.732
CRHBP
Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.
    
   0.711
SELENBP1
Selenium binding protein 1.
    
   0.704
MRPS22
Mitochondrial ribosomal protein S22.
   
  
 0.703
SCAF4
SR-related CTD associated factor 4.
    
   0.699
DDX28
DEAD-box helicase 28.
   
  
 0.693
METTL17
Methyltransferase like 17.
      
 0.688
MRPL41
Mitochondrial ribosomal protein L41.
      
 0.684
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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