Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KCTD5Potassium channel tetramerization domain containing 5. (232 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.846
KCTD2
Potassium channel tetramerization domain containing 2.
    
 
 0.764
KCTD9
Potassium channel tetramerization domain containing 9.
    
 
 0.713
DMC1
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
    
   0.708
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
      
 0.680
SCML2
Scm polycomb group protein like 2.
      
 0.653
IGFBP2
Insulin like growth factor binding protein 2.
      
 0.651
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.621
H3AMY7_LATCH
Uncharacterized protein.
      
 0.611
ARRDC1
Arrestin domain containing 1.
    
   0.607
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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