Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)    
Predicted Functional Partners:
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.999
MAPK9
Mitogen-activated protein kinase.
   
 0.998
MAPK8
Mitogen-activated protein kinase.
   
 0.994
FOSL2
FOS like 2, AP-1 transcription factor subunit.
   
 0.991
ATF3
Activating transcription factor 3.
   
 0.989
JUND
BZIP domain-containing protein.
   
 0.987
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
   
 0.975
IL6
Uncharacterized protein.
   
 0.974
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.973
MAPK14
Mitogen-activated protein kinase.
    
 0.973
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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