STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (214 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
     
 0.996
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
     
 0.977
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
     
 0.977
CERS5
Ceramide synthase 5.
     
 0.947
CERS1
Ceramide synthase 1.
     
 0.947
CERS2
Ceramide synthase 2.
     
 0.947
CERS3
Ceramide synthase 3.
     
 0.947
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
 
 0.945
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.945
LOC102355762
Lipid_DES domain-containing protein.
   
 
 0.945
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.