Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)    
Predicted Functional Partners:
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
0.989
DHRS11
Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.986
CYP19A1
Cytochrome P450 family 19 subfamily A member 1.
    
 0.958
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
  
 
 0.956
SRD5A3
Steroid 5 alpha-reductase 3.
     
 0.946
H2ZVK5_LATCH
Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.
   
 0.945
LOC102345588
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
   
 
 0.944
HSD17B8
Hydroxysteroid 17-beta dehydrogenase 8.
  
 
 0.940
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
     
 0.936
HSD17B12
Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.936
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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