Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A7N7_LATCHGF_recep_IV domain-containing protein. (99 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.912
ITSN2
Intersectin 2.
    
 0.814
GAB1
GRB2 associated binding protein 1.
    
 0.793
RNF41
Ring finger protein 41.
    
 0.791
CBLB
Cbl proto-oncogene B.
    
 0.777
H3AWW7_LATCH
Uncharacterized protein.
    
 0.777
CBL
Cbl proto-oncogene.
    
 0.777
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.776
STAT3
Signal transducer and activator of transcription.
    
 0.762
ESR2
Estrogen receptor 2.
    
 0.758
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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