Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DSPDesmoplakin. (2623 aa)    
Predicted Functional Partners:
PKP2
Uncharacterized protein.
   
 0.991
LOC102361492
Uncharacterized protein.
  
 0.985
PKP1
Plakophilin 1.
   
 0.985
LOC102361769
Uncharacterized protein.
  
 0.951
JUP
Junction plakoglobin.
   
 0.914
H3A0S9_LATCH
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.788
ITGB4
Integrin beta.
   
 0.764
CTNNB1
Catenin beta 1.
   
 0.689
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
 0.673
CAMSAP1
Calmodulin regulated spectrin associated protein 1.
    
 
 0.600
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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