OPRK1 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

OPRK1

Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (300 aa)

Predicted Functional Partners:

PDYN

0.977

PNOC

0.977

POMC

0.976

PENK

0.972

OPRD1

0.951

OPRL1

0.946

OGFRL1

0.937

GNG2

0.885

LOC102361424

0.875

GNAI3

0.875

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAI3	GNG2	ENSLACP00000020114	ENSLACP00000018370	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.907
GNAI3	LOC102361424	ENSLACP00000020114	ENSLACP00000013070	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.	0.900
GNAI3	OGFRL1	ENSLACP00000020114	ENSLACP00000005589	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Opioid growth factor receptor like 1.	0.650
GNAI3	OPRD1	ENSLACP00000020114	ENSLACP00000003449	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	0.851
GNAI3	OPRK1	ENSLACP00000020114	ENSLACP00000005672	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.	0.875
GNAI3	OPRL1	ENSLACP00000020114	ENSLACP00000012012	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Opioid related nociceptin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.694
GNAI3	POMC	ENSLACP00000020114	ENSLACP00000013290	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Proopiomelanocortin.	0.428
GNG2	GNAI3	ENSLACP00000018370	ENSLACP00000020114	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.907
GNG2	LOC102361424	ENSLACP00000018370	ENSLACP00000013070	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.	0.907
GNG2	OGFRL1	ENSLACP00000018370	ENSLACP00000005589	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Opioid growth factor receptor like 1.	0.650
GNG2	OPRD1	ENSLACP00000018370	ENSLACP00000003449	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	0.968
GNG2	OPRK1	ENSLACP00000018370	ENSLACP00000005672	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.	0.885
GNG2	OPRL1	ENSLACP00000018370	ENSLACP00000012012	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Opioid related nociceptin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.720
GNG2	PDYN	ENSLACP00000018370	ENSLACP00000000398	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Prodynorphin.	0.577
GNG2	PENK	ENSLACP00000018370	ENSLACP00000000197	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Proenkephalin.	0.521
GNG2	PNOC	ENSLACP00000018370	ENSLACP00000003036	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Prepronociceptin a.	0.513
GNG2	POMC	ENSLACP00000018370	ENSLACP00000013290	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Proopiomelanocortin.	0.983
LOC102361424	GNAI3	ENSLACP00000013070	ENSLACP00000020114	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.900
LOC102361424	GNG2	ENSLACP00000013070	ENSLACP00000018370	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.907
LOC102361424	OGFRL1	ENSLACP00000013070	ENSLACP00000005589	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.	Opioid growth factor receptor like 1.	0.650