Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC10Uncharacterized protein. (244 aa)    
Predicted Functional Partners:
LOC102362853
Si:ch73-362m14.4.
    
 0.749
LOC102364878
PRKG1_interact domain-containing protein.
    
 0.732
CDC42EP3
CDC42 effector protein 3.
    
 0.654
GLIPR1
GLI pathogenesis related 1; Belongs to the CRISP family.
      
 0.591
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
 0.548
LOC102359959
ZnMc domain-containing protein.
     
 0.546
LOC102360231
ZnMc domain-containing protein.
     
 0.546
LOC102360492
ZnMc domain-containing protein.
     
 0.546
LRRTM4
Leucine rich repeat transmembrane neuronal 4.
  
   
 0.534
LRRTM3
Leucine rich repeat transmembrane neuronal 3.
  
   
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]