Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM160A2Family with sequence similarity 160 member A2. (1117 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
    
 
 0.911
HOOK3
Hook microtubule tethering protein 3.
    
 
 0.905
HOOK1
Hook microtubule tethering protein 1.
    
 
 0.820
HOOK2
Hook microtubule tethering protein 2.
    
 
 0.811
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
    
   0.761
LOC102358329
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
   0.667
GPR78
G protein-coupled receptor 78b.
      
 0.614
BRINP1
BMP/retinoic acid inducible neural specific 1.
      
 0.491
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.454
WDR35
WD repeat-containing protein 35.
      
 0.454
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.