Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UVSSAUV-stimulated scaffold protein A. (751 aa)    
Predicted Functional Partners:
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 0.998
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.996
DDB1
Damage specific DNA binding protein 1.
    
 0.938
ELOF1
Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.
    
 
 0.926
RBX1
Ring-box 1.
    
 0.903
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.902
XAB2
XPA binding protein 2.
     
 0.863
USP40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
    
 0.861
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.846
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.846
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (44%) [HD]