Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIZUncharacterized protein. (690 aa)    
Predicted Functional Partners:
SCLT1
Sodium channel and clathrin linker 1.
    
  0.963
H3BCG1_LATCH
SET domain-containing protein.
    
  0.782
FANCM
FA complementation group M.
    
 
 0.772
TMTC4
Transmembrane O-mannosyltransferase targeting cadherins 4.
    
 0.634
AP4E1
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
    
 
 0.591
PRDM1
SET domain-containing protein.
    
  0.577
SLC4A10
Anion exchange protein.
    
 0.568
BTK
Tyrosine-protein kinase.
    
  0.564
BMX
Tyrosine-protein kinase.
    
  0.564
MFHAS1
Malignant fibrous histiocytoma amplified sequence 1.
    
 0.563
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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