Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR61WD_REPEATS_REGION domain-containing protein. (305 aa)    
Predicted Functional Partners:
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component.
    
 0.994
CDC73
Cell division cycle 73.
    
 0.993
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.992
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.988
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.979
TTC37
Tetratricopeptide repeat domain 37.
   
 0.965
H3A117_LATCH
Helicase ATP-binding domain-containing protein.
    
 0.958
TTC33
Tetratricopeptide repeat domain 33.
    
  0.858
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 
 0.847
HBS1L
HBS1 like translational GTPase.
    
 0.837
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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