Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOX18SRY-box transcription factor 18. (427 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.844
TFAP2C
Transcription factor AP-2 gamma.
   
 0.767
H3BCG1_LATCH
SET domain-containing protein.
    
 0.750
LOC102362664
POU domain protein.
    
 0.688
LOC102355666
POU domain protein.
    
 0.688
CXCR4
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.671
GATA6
GATA binding protein 6.
   
 0.670
NAT8L
N-acetyltransferase 8 like.
      
 0.649
LEF1
Lymphoid enhancer binding factor 1.
    
 0.648
EWSR1
EWS RNA binding protein 1.
    
 
 0.640
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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