Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM192Transmembrane protein 192. (267 aa)    
Predicted Functional Partners:
LAMP2
Lysosomal associated membrane protein 2.
    
 0.980
LAMP1
Lysosomal associated membrane protein 1.
    
 0.890
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
   
 0.811
SPRYD4
SPRY domain containing 4.
   
  0.759
RAB7A
RAB7A, member RAS oncogene family.
    
 0.732
ASB8
Ankyrin repeat and SOCS box containing 8.
    
 0.656
RTRAF
RNA transcription, translation and transport factor.
      
 0.641
GRAMD1C
GRAM domain containing 1C.
   
 0.637
TMEM167A
Protein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family.
      
 0.629
NIPAL4
NIPA like domain containing 4.
      
 0.627
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.