Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHMP5Charged multivesicular body protein 5. (220 aa)    
Predicted Functional Partners:
VTA1
Vta1 domain-containing protein.
   
 0.999
CHMP2A
Charged multivesicular body protein 2A.
   
 0.995
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.993
VPS4A
Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.
   
 0.993
LOC102356960
Charged multivesicular body protein 3.
   
 0.986
IST1
IST1 factor associated with ESCRT-III.
   
 
 0.973
CHMP2B
Charged multivesicular body protein 2B.
   
 0.973
CHMP6
Charged multivesicular body protein 6.
   
 0.956
BROX
BRO1 domain and CAAX motif containing.
   
 0.942
CHMP4B
Charged multivesicular body protein 4B.
   
 0.932
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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