STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APCAPC regulator of WNT signaling pathway. (2802 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.963
JUP
Junction plakoglobin.
   
 0.927
AXIN1
Axin 1.
    
 0.909
AXIN2
Axin 2.
    
 0.909
AMER1
APC membrane recruitment protein 1.
    
 0.904
GSK3A
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.863
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.863
H3A8H2_LATCH
Uncharacterized protein.
    
 0.797
ARHGEF4
Rho guanine nucleotide exchange factor 4.
   
 
 0.776
UCKL1
Uridine-cytidine kinase 1 like 1.
   
 0.771
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.