STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102356298Uncharacterized protein. (236 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
     
 0.982
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.963
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.957
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.946
LRP2
LDL receptor related protein 2.
     
 0.901
PTCH2
Patched 2.
     
 0.721
GAS2
Growth arrest specific 2.
      
 0.595
PARM1
Uncharacterized protein.
      
 0.571
CDON
Cell adhesion associated, oncogene regulated.
      
 0.559
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.545
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.