Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A7X3_LATCHIg-like domain-containing protein. (232 aa)    
Predicted Functional Partners:
REL
REL proto-oncogene, NF-kB subunit.
   
 0.732
H3B111_LATCH
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
 0.732
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.716
H3B6K7_LATCH
IKKbetaNEMObind domain-containing protein.
    
 0.716
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
   
 0.679
LIPE
Lipase E, hormone sensitive type.
    
 
 0.613
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
     
 0.605
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.602
SCARF1
Scavenger receptor class F member 1.
     
 0.590
RPS27A
Ribosomal protein S27a.
    
  0.588
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.