Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLBKlotho beta. (1027 aa)    
Predicted Functional Partners:
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.917
FGFR4
Fibroblast growth factor receptor.
    
 0.873
FGFR1
Fibroblast growth factor receptor.
    
 0.813
FGF19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.799
FGFR2
Fibroblast growth factor receptor.
    
 0.777
GCNA
Germ cell nuclear acidic peptidase.
      
 0.698
FGFR3
Fibroblast growth factor receptor.
    
 0.697
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
 
    
 0.674
FLAD1
Flavin adenine dinucleotide synthetase 1.
      
 0.657
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
      
 0.644
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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