TBP protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TBP

TATA-box binding protein. (301 aa)

Predicted Functional Partners:

H3AV84_LATCH

0.982

GTF2B

0.975

TAF12

0.966

TAF3

0.965

TAF2

0.965

TAF10

0.963

TAF9

0.962

BRF1

0.962

TAF6

0.961

TAF11

0.960

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRF1	GTF2B	ENSLACP00000018052	ENSLACP00000010617	BRF1 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIB.	0.791
BRF1	TBP	ENSLACP00000018052	ENSLACP00000005765	BRF1 RNA polymerase III transcription initiation factor subunit.	TATA-box binding protein.	0.962
GTF2B	BRF1	ENSLACP00000010617	ENSLACP00000018052	General transcription factor IIB.	BRF1 RNA polymerase III transcription initiation factor subunit.	0.791
GTF2B	H3AV84_LATCH	ENSLACP00000010617	ENSLACP00000013555	General transcription factor IIB.	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.978
GTF2B	TAF10	ENSLACP00000010617	ENSLACP00000004533	General transcription factor IIB.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.949
GTF2B	TAF11	ENSLACP00000010617	ENSLACP00000015974	General transcription factor IIB.	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.962
GTF2B	TAF12	ENSLACP00000010617	ENSLACP00000014165	General transcription factor IIB.	TATA-box binding protein associated factor 12.	0.962
GTF2B	TAF2	ENSLACP00000010617	ENSLACP00000011652	General transcription factor IIB.	TATA-box binding protein associated factor 2.	0.948
GTF2B	TAF3	ENSLACP00000010617	ENSLACP00000005947	General transcription factor IIB.	TATA-box binding protein associated factor 3.	0.908
GTF2B	TAF6	ENSLACP00000010617	ENSLACP00000003345	General transcription factor IIB.	TATA-box binding protein associated factor 6.	0.947
GTF2B	TAF9	ENSLACP00000010617	ENSLACP00000009355	General transcription factor IIB.	TATA-box binding protein associated factor 9.	0.984
GTF2B	TBP	ENSLACP00000010617	ENSLACP00000005765	General transcription factor IIB.	TATA-box binding protein.	0.975
H3AV84_LATCH	GTF2B	ENSLACP00000013555	ENSLACP00000010617	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIB.	0.978
H3AV84_LATCH	TAF10	ENSLACP00000013555	ENSLACP00000004533	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.995
H3AV84_LATCH	TAF11	ENSLACP00000013555	ENSLACP00000015974	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
H3AV84_LATCH	TAF12	ENSLACP00000013555	ENSLACP00000014165	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 12.	0.998
H3AV84_LATCH	TAF2	ENSLACP00000013555	ENSLACP00000011652	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 2.	0.999
H3AV84_LATCH	TAF3	ENSLACP00000013555	ENSLACP00000005947	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 3.	0.998
H3AV84_LATCH	TAF6	ENSLACP00000013555	ENSLACP00000003345	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 6.	0.996
H3AV84_LATCH	TAF9	ENSLACP00000013555	ENSLACP00000009355	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 9.	0.995