Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A807_LATCHUncharacterized protein. (507 aa)    
Predicted Functional Partners:
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.970
LYN
Tyrosine-protein kinase.
   
 0.906
CD79A
CD79a molecule, immunoglobulin-associated alpha.
   
 
 0.847
SYK
Tyrosine-protein kinase.
   
 0.807
GRB2
Growth factor receptor bound protein 2.
    
 0.747
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.722
SIGLEC15
Sialic acid binding Ig like lectin 15.
    
 0.663
SIAE
Sialic acid acetylesterase.
      
 0.641
CD40LG
CD40 ligand; Belongs to the tumor necrosis factor family.
   
  
 0.579
ATG16L1
Autophagy related 16 like 1.
      
 0.504
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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