Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A812_LATCHUncharacterized protein. (193 aa)    
Predicted Functional Partners:
CLDN7
Claudin 7b.
  
  0.814
LOC102346705
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
 
 
0.746
CLDN12
Claudin 12.
     
 0.741
LOC102360103
Uncharacterized protein.
  
  
  0.741
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
 0.739
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.739
LOC106705730
Uncharacterized protein.
  
 
 
0.732
CLDN1
Claudin 1.
  
 
0.714
LOC102352367
Uncharacterized protein.
  
  
 
0.710
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
 
 
0.707
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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