STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (265 aa)    
Predicted Functional Partners:
SMC5
AAA_23 domain-containing protein.
    
 0.999
LOC102350471
MAGE domain-containing protein.
   
 0.999
SMC6
Structural maintenance of chromosomes 6.
    
 0.999
LOC102345952
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.999
H3BDY7_LATCH
Uncharacterized protein.
    
 0.973
SMC3
Structural maintenance of chromosomes protein.
    
 0.886
SMC1A
Structural maintenance of chromosomes protein.
    
 0.860
SMC1B
Structural maintenance of chromosomes protein.
    
 0.860
LOC102366597
SMC_N domain-containing protein.
    
 0.820
SMC4
Structural maintenance of chromosomes protein.
    
 0.820
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.