STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (397 aa)    
Predicted Functional Partners:
H2ZSK8_LATCH
TYR_PHOSPHATASE_2 domain-containing protein.
    
 0.799
EPM2A
EPM2A glucan phosphatase, laforin.
    
 0.799
ADAM23
ADAM metallopeptidase domain 23.
      
 0.699
FSD1L
Fibronectin type III and SPRY domain containing 1 like.
      
 0.669
FSD1
Fibronectin type III and SPRY domain containing 1.
      
 0.669
FSD2
Fibronectin type III and SPRY domain containing 2.
      
 0.669
BSPRY
B-box and SPRY domain containing.
      
 0.668
RNF207
Ring finger protein 207.
      
 0.656
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
    
 
 0.577
NEU1
Neuraminidase 1.
      
 0.552
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.