Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTA3Metastasis associated 1 family member 3. (438 aa)    
Predicted Functional Partners:
CHD4
Chromodomain helicase DNA binding protein 4a.
   
 0.955
GATAD2B
GATA zinc finger domain containing 2B.
   
 0.953
GATAD2A
GATA zinc finger domain containing 2A.
   
 0.945
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.904
MTA1
Metastasis associated 1.
  
  
0.904
MBD2
Methyl-CpG binding domain protein 2.
   
 0.885
MBD3
Methyl-CpG binding domain protein 3a.
   
 0.885
CHD3
Chromodomain helicase DNA binding protein 3.
   
 0.876
M3XHQ8_LATCH
Uncharacterized protein.
   
 0.876
RBBP7
WD_REPEATS_REGION domain-containing protein.
   
 0.843
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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