Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM189BFamily with sequence similarity 189 member B. (682 aa)    
Predicted Functional Partners:
WWOX
WW domain containing oxidoreductase.
    
 
 0.934
ITCH
E3 ubiquitin-protein ligase.
    
 0.804
M3XI64_LATCH
Uncharacterized protein.
    
 
 0.740
WWP1
E3 ubiquitin-protein ligase.
    
 0.738
ANKRD13D
Ankyrin repeat domain 13D.
    
   0.658
N4BP1
NEDD4 binding protein 1.
      
 0.636
SYNRG
Synergin gamma.
    
 0.614
NDFIP2
Nedd4 family interacting protein 2.
   
  
 0.598
RAB3IL1
RAB3A interacting protein like 1.
    
 0.597
CUEDC1
CUE domain containing 1.
    
   0.565
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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