Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1892 aa)    
Predicted Functional Partners:
RAB11FIP2
RAB11 family interacting protein 2.
   
 0.835
RAB27A
RAB27A, member RAS oncogene family.
    
 0.793
RAB11FIP1
RAB11 family interacting protein 1.
   
 0.767
LOC102357106
RAB11a, member RAS oncogene family, like.
   
 0.765
RAB11A
RAB11A, member RAS oncogene family.
   
 0.765
LOC102363089
RAB11B, member RAS oncogene family, b.
   
 0.765
EXOC4
Exocyst complex component 4.
   
 0.745
RAB11B
RAB11B, member RAS oncogene family.
   
 0.732
MLPH
Melanophilin.
    
 0.697
ARPC2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
  0.677
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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