Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC102348367ZnMc domain-containing protein; Belongs to the peptidase M10A family. (559 aa)    
Predicted Functional Partners:
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.713
CDC42EP3
CDC42 effector protein 3.
      
 0.655
LOC102362993
Uncharacterized protein.
      
 0.654
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.612
LOC102361064
NTR domain-containing protein.
   
 0.573
Lach-UB-05-2
Ig-like domain-containing protein.
      
 0.525
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 0.497
PCSK4
Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.
    
 0.497
TIMP4
TIMP metallopeptidase inhibitor 4.
    
 0.493
LOC102351431
Uncharacterized protein.
   
 0.470
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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