Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FDX2Ferredoxin 2. (182 aa)    
Predicted Functional Partners:
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
 
 0.960
NFS1
NFS1 cysteine desulfurase.
 
 0.948
FADS6
Fatty acid desaturase 6.
    
 0.924
FDXR
NADPH:adrenodoxin oxidoreductase, mitochondrial.
    
 0.924
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.863
SCLY
Selenocysteine lyase.
  
 0.854
NDUFV2
NADH:ubiquinone oxidoreductase core subunit V2.
  
 
 0.840
ISCA1
Iron-sulfur cluster assembly 1.
  
 0.839
PALB2
PALB2_WD40 domain-containing protein.
   
 0.828
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8.
  
 
 0.819
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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