Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHMP4BCharged multivesicular body protein 4B. (225 aa)    
Predicted Functional Partners:
CHMP6
Charged multivesicular body protein 6.
   
 0.991
PDCD6IP
Programmed cell death 6 interacting protein.
   
 0.987
CHMP7
Charged multivesicular body protein 7.
    
0.985
CHMP1B
Charged multivesicular body protein 1B.
   
 0.972
CHMP1A
Charged multivesicular body protein 1A.
   
 0.972
CHMP2A
Charged multivesicular body protein 2A.
   
 0.961
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.957
CHMP2B
Charged multivesicular body protein 2B.
   
 0.945
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.944
LOC102356960
Charged multivesicular body protein 3.
   
 0.943
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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