STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPCS2Signal peptidase complex subunit 2. (173 aa)    
Predicted Functional Partners:
SPCS1
Signal peptidase complex subunit 1.
   
 0.986
SPCS3
Signal peptidase complex subunit 3.
   
 0.985
SEC11C
Signal peptidase complex catalytic subunit SEC11.
   
 0.919
SEC11A
Signal peptidase complex catalytic subunit SEC11.
   
 0.919
GRP
Gastrin-releasing peptide.
   
 0.879
CPE
Carboxypeptidase E.
      
 0.766
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.743
IMMP2L
Inner mitochondrial membrane peptidase subunit 2.
   
 0.733
ITFG2
Integrin alpha FG-GAP repeat containing 2.
   
 0.733
XRCC4
X-ray repair cross complementing 4.
   
 0.733
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.