Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A8P8_LATCHDUF4502 domain-containing protein. (165 aa)    
Predicted Functional Partners:
SWSAP1
Uncharacterized protein.
    
 
 0.962
ZSWIM7
Zinc finger SWIM-type containing 7.
    
   0.807
FIGN
Fidgetin, microtubule severing factor; Belongs to the AAA ATPase family.
    
 0.668
FIGNL1
Fidgetin like 1; Belongs to the AAA ATPase family.
    
 0.668
SPAST
Spastin; Belongs to the AAA ATPase family.
    
 0.668
FIGNL2
Fidgetin like 2.
    
 0.668
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.641
MCM4
DNA helicase; Belongs to the MCM family.
      
 0.627
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
      
 0.615
DHFR
Dihydrofolate reductase.
      
 0.611
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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