Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPP1R42Protein phosphatase 1 regulatory subunit 42. (252 aa)    
Predicted Functional Partners:
COPS4
COP9 signalosome subunit 4.
   
 0.956
COPS6
COP9 signalosome subunit 6.
   
 0.955
COPS2
COP9 signalosome subunit 2.
   
 0.952
COPS3
COP9 signalosome subunit 3.
   
 0.945
COPS8
COP9 signalosome subunit 8.
   
 0.941
GPS1
G protein pathway suppressor 1.
   
 0.937
COPS7B
COP9 signalosome subunit 7B.
   
 0.933
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.918
DDB1
Damage specific DNA binding protein 1.
    
 0.900
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.889
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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