STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1R42Protein phosphatase 1 regulatory subunit 42. (252 aa)    
Predicted Functional Partners:
COPS4
COP9 signalosome subunit 4.
   
 0.981
COPS6
COP9 signalosome subunit 6.
   
 0.980
COPS2
COP9 signalosome subunit 2.
   
 0.979
COPS3
COP9 signalosome subunit 3.
   
 0.977
COPS8
COP9 signalosome subunit 8.
   
 0.976
GPS1
G protein pathway suppressor 1.
   
 0.975
COPS7B
COP9 signalosome subunit 7B.
    
 0.972
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.968
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.947
CUL2
Cullin 2; Belongs to the cullin family.
   
 0.922
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.