STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPARTSpartin. (664 aa)    
Predicted Functional Partners:
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.910
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.732
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.707
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin.
      
 0.697
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.685
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.685
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.627
TOR4A
Torsin family 4 member A.
      
 0.617
NIPA1
NIPA magnesium transporter 1.
   
  
 0.577
TRIM45
Tripartite motif containing 45.
      
 0.552
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.