Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPARTSpartin. (664 aa)    
Predicted Functional Partners:
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.969
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.969
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.931
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.791
TOR4A
Torsin family 4 member A.
      
 0.767
NIPA1
NIPA magnesium transporter 1.
      
 0.710
TRIM45
Tripartite motif containing 45.
      
 0.677
WWOX
WW domain containing oxidoreductase.
    
   0.649
SUMF1
Sulfatase modifying factor 1.
    
 
 0.642
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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