Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FHDC1FH2 domain containing 1. (1130 aa)    
Predicted Functional Partners:
PLEK
Pleckstrin.
      
 0.778
PFN4
Profilin; Belongs to the profilin family.
    
 0.776
DVL3
Dishevelled segment polarity protein 3.
    
 0.686
DVL2
Dishevelled segment polarity protein 2.
    
 0.686
DVL1
Dishevelled segment polarity protein 1.
    
 0.686
ARHGEF4
Rho guanine nucleotide exchange factor 4.
    
 
 0.686
USH1C
USH1 protein network component harmonin.
      
 0.641
GRID2IP
Grid2 interacting protein.
    
 
0.631
RHOD
Uncharacterized protein.
    
 0.626
RHOF
Ras homolog family member F, filopodia associated.
    
 0.626
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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