Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SATB1DNA-binding protein SATB. (792 aa)    
Predicted Functional Partners:
CASP6
Caspase 6; Belongs to the peptidase C14A family.
    
 0.728
LOC102347040
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.716
LOC102365863
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.716
LOC102350007
Small ubiquitin-related modifier.
    
 0.658
PIAS4
Protein inhibitor of activated STAT 4.
    
  0.632
TBR1
T-box brain transcription factor 1.
   
 
 0.623
PAX6
Paired box 6.
      
 0.622
PIAS1
Protein inhibitor of activated STAT 1.
    
 0.614
PIAS3
Protein inhibitor of activated STAT 3.
    
 0.614
H3B480_LATCH
Uncharacterized protein.
   
 
 0.599
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]